Robust fluidic connections to freestanding microfluidic hydrogels
نویسندگان
چکیده
منابع مشابه
Connections Matter: Channeled Hydrogels to Improve Vascularization
The use of cell-laden hydrogels to engineer soft tissue has been emerging within the past years. Despite, several newly developed and sophisticated techniques to encapsulate different cell types the importance of vascularization of the engineered constructs is often underestimated. As a result, cell death within a construct leads to impaired function and inclusion of the implant. Here, we discu...
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Current methods for engineering vascularized tissues rely primarily on the self-organization of vascular cells (endothelial cells, pericytes, and smooth muscle cells) or their progenitors in a scaffold and/or on the recruitment of new vessels via release of angiogenic factors [1,2]. While these approaches certainly accelerate the process of graft vascularization, they still require several days...
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ژورنال
عنوان ژورنال: Biomicrofluidics
سال: 2015
ISSN: 1932-1058
DOI: 10.1063/1.4921453